Recent work in Tuuli Lappalainen’s lab has shown that deleterious coding variants, when heterozygous, are found disproportionately on down regulated haplotypes when looking at allele specific […]

Improving our ability to predict health outcomes will substantially decrease the costs of health care while simultaneously improving health outcomes. Individuals who go to the hospital […]

Expression quantitative trait loci (eQTLs), variations in the genome that impact gene expression, are identified through eQTL studies that test for a relationship between single nucleotide […]

*Homo Neanderthalensis, adult male. Reconstruction based on Shanidar 1 by John Gurche. Photo credit: Smithsonian National Museum of Natural History   Modern Europeans on average have […]